Bio-Rad Laboratories, Inc., a global leader in life science research and clinical diagnostics, has unveiled its latest innovation: the TrailBlazer™ Tag and TrailBlazer StarBright™ Dye Label Kits. These kits offer a convenient method to label any antibody with Bio-Rad’s StarBright Dyes, making them ideal for use in flow cytometry and fluorescent western blot experiments.
Key Features of the TrailBlazer Kits
| Feature | Description |
|---|---|
| StarBright Dyes | Proprietary fluorescent nanoparticles offering exceptional brightness and narrow excitation/emission profiles. |
| SpyTag and SpyCatcher Technology | Innovative technology used to conjugate dyes to antibodies, ensuring high stability and minimal hands-on time. |
| Versatile Applications | Suitable for flow cytometry and fluorescent western blot experiments. |
| Multiple Dye Options | Access to StarBright Blue and StarBright Violet Dyes, with more options coming soon. |
How It Works
The TrailBlazer system employs Bio-Rad’s SpyTag and SpyCatcher technology to conjugate a dye to an antibody of choice. This enables researchers to design and generate bespoke, flexible high-plex panels for flow cytometry and easy multiplex integration for fluorescent western blots.
Benefits for Researchers
- Flexibility: The kits provide multiple label color palette options, allowing researchers to customize their experiments.
- Ease of Use: With an easy-to-follow protocol and minimal hands-on time, the kits offer a simple process resulting in consistent, high-quality conjugated antibodies.
- Compatibility: StarBright Dyes are compatible with most experimental protocols and flow cytometers, including the Bio-Rad ZE5 Cell Analyzer.
Applications
Bio-Rad’s range of StarBright Dyes, conjugated to flow-validated antibodies against key immunological targets, offers researchers exceptional brightness with narrow excitation and emission profiles for precise resolution. These dyes are designed to work seamlessly with the configuration of the ChemiDoc™ MP and ChemiDoc Go Imagers, facilitating bright, highly sensitive fluorescent detection with short exposure times.
Conclusion
The launch of the TrailBlazer Tag and TrailBlazer StarBright Dye Label Kits marks a significant advancement in antibody conjugation technology. By providing researchers with a versatile, easy-to-use solution for labeling antibodies, Bio-Rad continues to support the scientific community in achieving precise and reliable results in their experiments.
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